FOG2 coding variant Ser657Gly is associated with Coronary Microvascular Disease through altered hypoxia-mediated gene transcription
Marie A. Guerraty, Shefali S. Verma, Y.A. Ko, Michael A. McQuillan, Donna Conlon, John W. Tobias, Michael G. Levin, William R. Haury, C. Zhang, Renae Judy, PennMedicine Biobank, Sarah A. Tishkoff, Scott M. Damrauer, Zoltan Pierre Arany, Daniel James Rader
The paper identifies a FOG2 variant associated with coronary microvascular disease and shows it alters hypoxia-mediated gene transcription and angiogenesis.
medRxiv · May 22, 2023 · PreprintGenetic & Genomic Medicine