Promoter hijacking by primate LINC00473 disrupts an ancestral CREB-PDE10A feedback loop
Shelby J. Squires, Brandon S. Smith, Mukhayyo Sultonova, Emma J. Campbell, V. Shruthi Bandi, Brandon I. MacDonald, João A. Paulo, Adam P. W. Johnston, John Patrick Murphy, P. Joel Ross
The paper investigates how the primate-specific lncRNA LINC00473 disrupts an ancestral CREB-PDE10A feedback loop by hijacking its promoter.
bioRxiv · Oct 2, 2025 · PreprintMolecular Biology