Decomposing the subclonal structure of tumors with two-way mixture models on copy number aberrations
An‐Shun Tai, Chien-Hua Peng, Shih-Chi Peng, Wen‐Ping Hsieh
This paper introduces CloneDeMix, a two-way mixture model for analyzing copy number aberrations in tumors, revealing subclonal structure and mutation order with high accuracy.
PLoS ONE · Dec 12, 2018Peer-reviewedBioinformatics