An‐Shun Tai

The paper develops a sparse negative binomial classifier for RNA-seq data that adjusts for covariates and improves prediction accuracy and feature selection.

BayICE improves gene expression deconvolution by addressing limitations in cell type gene selection and unknown cell profile recovery, showing better performance in estimating cell proportions in cancer data.

This paper introduces CloneDeMix, a two-way mixture model for analyzing copy number aberrations in tumors, revealing subclonal structure and mutation order with high accuracy.