Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM genes in the blood of Alzheimer's disease patients
Risa Mitsumori, Kazuya Sakaguchi, Daichi Shigemizu, Taiki Mori, Shintaro Akiyama, Kouichi Ozaki, Shumpei Niida, Nobuyoshi Shimoda
The paper examines DNA methylation levels in AD-related genes in blood and finds lower methylation in CR1, CLU, and PICALM in AD patients, with potential diagnostic value.
PLoS ONE · Sep 29, 2020Peer-reviewedGenetic & Genomic Medicine