Author

Shriya Shivakumar

Bryn Mawr College

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:GWAS / association mapping· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Bárbara Domingues BitarelloiD· 1 shared Christopher S. ThomiD· 1 shared Madison B WilkeniD· 1 shared Phillip B. NicoliD· 1 shared Rafael A. IrizarryiD· 1 shared Victor Tsao· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Bárbara Domingues BitarelloORCID

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2 papers

Recent·Most cited

Spurious correlation inflates performance in single-cell perturbation prediction

Phillip B. Nicol, Shriya Shivakumar, Rafael A. Irizarry

The paper shows that performance metrics in single-cell perturbation prediction are inflated by reusing control cells, leading to overestimation of method effectiveness.

bioRxiv · Aug 11, 2026 · PreprintBioinformatics

Genetically influenced tobacco and alcohol use behaviors impact erythroid trait variation

Shriya Shivakumar, Madison B Wilken, Victor Tsao, Bárbara Domingues Bitarello, Christopher S. Thom

This study uses Mendelian randomization to show that genetic predisposition to smoke tobacco indirectly reduces red blood cell count by increasing alcohol intake.

PLoS ONE · Sep 5, 2024Peer-reviewedGenetic & Genomic Medicine