Nucleic acid turnover and lipid remodeling distinguish T cell activation and exhaustion states via label-free Raman spectroscopy
M. B. McDonald, Srilakshmi Premachandran, Shruthi Ravichandran, Loza F. Tadesse
This paper uses label-free Raman spectroscopy to distinguish T cell activation and exhaustion states with high accuracy, identifying nucleic acid turnover and lipid remodeling as key features.
ACS Sensors · Sep 12, 2026Peer-reviewedBiophysics