An N-Terminally Acetylated Degron Specifically Recognized by the CTLHMKLN1-FAM72A E3 Ubiquitin Ligase for Regulatory Protein Degradation
Maosheng Yang, Shuqi Yao, Zheng Fang, Wenjie Ren, Yanyang Yang, Qizhou Song, Wen Yang, Hui Wang
The paper identifies an N-terminal acetylated degron recognized by the CTLHMKLN1-FAM72A E3 ubiquitin ligase, revealing a specific motif and molecular mechanism for proteasomal degradation.
bioRxiv · Sep 22, 2026 · PreprintBiochemistry