Decoding glycosylation potential from protein structure across human glycoproteins with a multi-view recurrent neural network
Benjamin P. Kellman, Julien A. Mariethoz, Yujie Zhang, Sigal Shaul, Mia Alteri, Daniel R. Sandoval, Mia Jeffris, Erick Armingol, Bokan Bao, Frédérique Lisacek, Daniel Bojar, Nathan E. Lewis
The paper trains a hybrid neural network to predict N-glycosylation events and structures from protein sequences using glycosite-flanking data, demonstrating its ability to predict glycan composition and abundance.
bioRxiv · May 15, 2024 · PreprintBioinformatics