Mia Jeffris

Decoding glycosylation potential from protein structure across human glycoproteins with a multi-view recurrent neural network

The paper trains a hybrid neural network to predict N-glycosylation events and structures from protein sequences using glycosite-flanking data, demonstrating its ability to predict glycan composition and abundance.

Protein structure, a genetic encoding for glycosylation

The paper identifies a relationship between protein structure and glycan structure, introducing a glycoimpact matrix to predict glycosylation patterns and validate it through disease variants and engineered antibodies.