Genetic disruption of cutaneous de novo glucocorticoid synthesis: a CRISPR-Cas9 CYP11B1-knockout human epidermal model
Onur Parlak, Sihui Xu, Liu Yang, Kunal Das Mahapatra, Guanglin Niu
This paper creates a CRISPR-Cas9 CYP11B1-knockout human epidermal model to study the effects of blocking cutaneous glucocorticoid synthesis.
bioRxiv · Nov 4, 2026 · PreprintCell Biology