Dimerization of MilM is essential for catalyzing the pyridoxal-5'-phosphate (PLP)-dependent Cγ-hydroxylation of L-arginine during mildiomycin biosynthesis
Simita Das, Yashwanth Naik, Udita Mishra, Mahima Ganguly, Badri N. Dubey, Suvamay Jana, Nilkamal Mahanta
This paper investigates the dimerization and catalytic mechanism of MilM, a PLP-dependent enzyme involved in mildiomycin biosynthesis, revealing its role in substrate binding, catalysis, and product formation.
Biochemistry · May 15, 2026Peer-reviewedBiochemistry