Author

Simon Bache

Université de Sherbrooke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:long-read sequencing· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Karine ChoquetiD· 2 shared Anne-Marie Landry-VoyeriD· 1 shared Autum R. Baxter‐KoenigsiD· 1 shared François BachandiD· 1 shared L. Stirling ChurchmaniD· 1 shared Lauren Kwiatek· 1 shared Louis-Philippe Chaumont· 1 shared Salomé Sabatié· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersGenomics

Karine ChoquetORCID

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2 papers

Recent·Most cited

Coupled and independent functions of PABPN1 in RNA processing revealed by direct RNA nanopore sequencing

Simon Bache, Anne-Marie Landry-Voyer, Lauren Kwiatek, Salomé Sabatié, François Bachand, Karine Choquet

This study uses RNA nanopore sequencing to show that PABPN1 has distinct and independent functions in RNA processing, including alternative polyadenylation, splicing, and nuclear trafficking.

bioRxiv · Aug 28, 2026 · PreprintGenomics

Genetic regulation of nascent RNA maturation revealed by direct RNA nanopore sequencing

Karine Choquet, Louis-Philippe Chaumont, Simon Bache, Autum R. Baxter‐Koenigs, L. Stirling Churchman

This study uses direct RNA nanopore sequencing to analyze allele-specific pre-mRNA maturation in human lymphoblastoid cell lines, revealing splicing order differences and SNP-splicing associations.

Genome Research · Apr 1, 2025Peer-reviewedGenomics