A human in vitro neuronal model for studying homeostatic plasticity at the network level
Xiuming Yuan, Sofía Puvogel, Jon-Ruben van Rhijn, Ummi Ciptasari, Anna Esteve‐Codina, Mandy Meijer, Simon Rouschop, Eline van Hugte, Astrid R. Oudakker, Chantal Schoenmaker, Monica Frega, Dirk Schubert, Barbara Franke, Nael Nadif Kasri
This study uses human iPSC-derived neuronal networks to show that homeostatic plasticity involves network re-arrangement, increased excitability, and changes in gene expression related to extracellular matrix and cell communication.
Stem Cell Reports · Oct 19, 2023Peer-reviewedNeuroscience