Improved pathway reconstruction from RNA interference screens by exploiting off-target effects
Sumana Srivatsa, Jack Kuipers, Fabian Schmich, Simone Eicher, Mario Emmenlauer, Christoph Dehio, Niko Beerenwinkel
The paper improves pathway reconstruction from RNAi screens by incorporating off-target effects into nested effects models, enhancing network accuracy.
Bioinformatics · Apr 12, 2018Peer-reviewedBioinformatics