Machine learning-aided multidimensional phenotyping of Parkinson's disease patient stem cell-derived midbrain dopaminergic neurons
Aurore Vuidel, Loïc Cousin, Beatrice Weykopf, Simone Haupt, Zahra Hanifehlou, Nicolas Wiest-Daesslé, Michaela Segschneider, Michael Peitz, Arnaud Ogier, Laurent Brino, Oliver Brüstle, Peter Sommer, Johannes H. Wilbertz
The paper uses machine learning to classify Parkinson's disease patient-derived midbrain dopaminergic neurons based on multiple image-based phenotypes and identifies treatable targets.
bioRxiv · Mar 1, 2022 · PreprintNeuroscience