Elevated blood creatinine -a biomarker of renal function- associates with multiple metabolic perturbations in dogs
Claudia Ottka, Katariina Vapalahti, Ann‐Marie Määttä, Nanna Huuskonen, Sinikka Sarpanen, Liisa Jalkanen, Hannes Lohi
The paper identifies metabolic changes in dogs with elevated blood creatinine using NMR metabolomics, finding associations with several biomarkers and suggesting potential diagnostic and therapeutic targets.
bioRxiv · May 6, 2020 · PreprintMolecular Biology