Cognitive and Synaptic Impairment Induced by Deficiency of Autism Risk Gene Smarcc2 and its Rescue by Histone Deacetylase Inhibition
Pei Li, Siqi Men, Prachetas Jai Patel, Komal Saleem, Ping Zhong, Kin Wai Tam, Jian Feng, Zhen Yan
This study shows that Smarcc2 deficiency causes cognitive and synaptic impairments in mice, which can be rescued by HDAC inhibition.
Molecular Psychiatry · Aug 26, 2026Peer-reviewedNeuroscience