BioinformaticsbioRxivPreprint
Comprehensive benchmarking of somatic structural variant detection at ultra-low allele fractions
Yuwei Zhang, Adam C. English, Luis F. Paulin…·Fritz Joachim Sedlazeck
The paper benchmarks somatic structural variant detection at ultra-low allele fractions using synthetic data and evaluates 12 pipelines, finding long-read sequencing provides higher accuracy than short-read methods.
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