Author

Sofia Luella Heese

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Gilbert GallardoiD· 1 shared Isabelle LerayiD· 1 shared Shamulailatpam Shreedarshanee DeviiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperNeuroscience

Gilbert GallardoORCID

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1 paper

Recent·Most cited

Glutaminolysis Fuels Reactive Astrocytes, Exacerbating Amyloid Pathology in Alzheimer's Disease.

Shamulailatpam Shreedarshanee Devi, Sofia Luella Heese, Isabelle Leray, Gilbert Gallardo

This study shows that reactive astrocytes in Alzheimer's disease use glutamine metabolism to worsen amyloid pathology, and blocking this process reduces amyloid burden in mice.

bioRxiv · Jun 12, 2025 · PreprintNeuroscience