Mapping the GCK-GKRP interaction landscape using deep mutational scanning by reverse two-hybrid screening
Sarah K. Gersing, Sofie Dahl, Kresten Lindorff‐Larsen, Rasmus Hartmann‐Petersen
The paper characterizes GCK variants' effects on GKRP interaction using deep mutational scanning, identifying variants that specifically perturb interactions and reveal allosteric effects.
bioRxiv · Jan 15, 2026 · PreprintBiochemistry