Author

Sonya Zhang

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alina Yang· 2 shared Da HuoiD· 2 shared Jin-Chong XuiD· 2 shared Ted M. DawsoniD· 2 shared Valina Lynn DawsoniD· 2 shared Yuejia Huang· 2 shared C. Korin BulleniD· 1 shared Haohui Fang· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Alina Yang

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2 papers

Recent·Most cited

Spatially Organized IGF1 mTOR Signaling Controls Human Forebrain Progenitor Fate Through Coordinated Transcriptional and Translational Programs

Kadia Lisst, Da Huo, Stephen M. Eacker, Sonya Zhang, Alina Yang, Yuejia Huang, Ted M. Dawson, Valina Lynn Dawson, Jin-Chong Xu

This study identifies a spatially organized IGF1-mTOR signaling mechanism in human forebrain progenitors that regulates proliferation and fate through transcriptional and translational control.

bioRxiv · May 8, 2025 · PreprintNeuroscience

APOE genotype confers context dependent neurovascular vulnerability in immune-vascularized human forebrain organoids

Haohui Fang, Xiangyu Liao, C. Korin Bullen, Ruoyan Pu, Hu Wang, Juliana Condoleo, Sueanne Cheat, Xueyi Chen, Yanjun Zhang, Sonya Zhang, Da Huo, Kadia Lissit, Alina Yang, Kateri Jarvis, Stewart Neifert, , Jinchong Xu

This study shows that APOE genotype affects neurovascular vulnerability in human forebrain organoids under viral stress, with APOE2/2 and APOE4/4 showing distinct inflammatory and vascular responses.

bioRxiv · May 8, 2025 · PreprintNeuroscience