Protease mimicry: dissecting the ester bond crosslinking mechanics in bacterial adhesin proteins
Y. Yosaatmadja, Vanessa Ung, Xinlu Liu, Yixuan Zhao, Julia K. Wardega, Aria Shetty, Sophie Schoensee, Ivanhoe K. H. Leung, J.R. Keown, David C. Goldstone, Edward N. Baker, Paul G. Young, Davide Mercadante, Christopher John Squire
The paper investigates the ester bond crosslinking mechanism in bacterial adhesin proteins, confirming a protease-like mechanism through structural, functional, and computational analyses.
Protein Science · Jul 26, 2025Peer-reviewedBiochemistry