Strand Displacement Activity of Mimiviral Polymerase X Enables Rapid Detection of Sequence-Specific DNA Targets
Apoorva S. Raman, Shailesh B. Lad, Soumyadeep Mandal, Debjani Paul, Kiran R. Kondabagil
The paper demonstrates a DNA detection method using Mimiviral polymerase X (mvPolX) that is sequence-specific and sensitive, capable of detecting as few as 10 copies of target DNA in 15 minutes.
bioRxiv · Jun 10, 2026 · PreprintMolecular Biology