High throughput screening of a new fluorescent G-quadruplex ligand having telomerase inhibitory activity in human A549 cells
Sourav Ghosh, Debapriya De, Victor Banerjee, Soumyajit Biswas, Utpal Ghosh
The paper screens a set of compounds from the ZINC database to identify a G-quadruplex ligand with telomerase inhibitory activity in human A549 cells, finding one compound with significant anti-telomerase effects and cytotoxicity.
Nucleosides Nucleotides & Nucleic Acids · Mar 15, 2023Peer-reviewedMolecular Biology