Expansion of human centromeric arrays in cells undergoing break-induced replication
Soyeon Showman, Paul B. Talbert, Yiling Xu, Richard O. Adeyemi, Steven Henikoff
The paper shows centromeric arrays can expand and contract in somatic cell divisions, with expansion favored, and identifies RAD52 and PIF1 as required for array changes via break-induced replication.
Cell Reports · Feb 29, 2024Peer-reviewedGenetics