Islet-antigen reactive B cells display a unique phenotype and BCR repertoire in autoantibody positive and recent-onset type 1 diabetes patients
Catherine A. Nicholas, Fatima A. Tensun, Spencer A. Evans, Kevin P. Toole, Jessica E. Prendergast, HALI C. BRONCUCIA, Jay R. Hesselberth, Peter A. Gottlieb, Kristen L. Wells, Mia J. Smith
The paper identifies unique phenotypic and BCR repertoire features of pancreatic islet antigen-reactive B cells in prediabetic and recent-onset type 1 diabetes individuals compared to non-diabetic donors.
Cell Reports · Mar 19, 2025Peer-reviewedImmunology