Conformation of the Catalytic Lysine is a Key Determinant of 2-Deoxyribose-5-phosphate Aldolase (DERA) Stereoselectivity
Srita Dutta, Ananya Nayak, Kodru Jeevani, Saravanan Thangavelu, Jagannath Mondal, Anand T. Vaidya
This study identifies the conformation of catalytic lysine as a key determinant of DERA stereoselectivity through structural and biochemical analyses.
bioRxiv · Jul 27, 2026 · PreprintBiochemistry