Author
Italian Institute of Technology
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Barry A. Chioza, Stefania S S Policicchio, Joe Burrage…·Emma Louise Dempster
The paper introduces optimized fluorescence-activated nuclei sorting (FANS) protocols to isolate cell-type-specific nuclei from human and mouse brain tissue for multi-omic analysis.
Alice Lambolez, Pelin Sahlén, Wenjing Kang…·Giuseppe Testa
The paper maps RNA-DNA interactions in 16 human cell types, showing cell-type-specific and dynamic networks that correlate with gene regulation and disease traits.
Szi Kay Leung, Emma Walker, Stefania S S Policicchio…·Jonathan S. Mill
The paper identifies DNA methylation changes in transgenic mouse models of Alzheimer's disease, showing distinct patterns for tau and amyloid-beta pathology and some overlap with human AD data.
Emma Walker, Emma Louise Dempster, Alice Franklin…·Eilis J. Hannon
The paper provides guidance for designing and analyzing cell-type specific epigenetic epidemiology studies using DNA methylation data from purified cell populations.
Eilis J. Hannon, Emma Louise Dempster, Jonathan P. Davies…·Jonathan S. Mill
The paper develops and validates deconvolution models using DNA methylation data to estimate cell-type proportions in the human cortex, finding glial cells are twice as abundant as neurons and linking cell-type proportions to Alzheimer's disease neuropathology.
Gemma L. Shireby, Emma Louise Dempster, Stefania S S Policicchio…·Jonathan S. Mill
The paper identifies DNA methylation signatures in Alzheimer's disease cortex, showing most changes are driven by non-neuronal cell types.