The tetraspanin disc proteins, peripherin-2 and ROM1, facilitate CNG channel localization to the rod outer segment
Molly T. Thorson, Stephanie E. Wei, Junseo Park, Jorge Y. Martínez-Márquez, David G. Ball, Jason R. Willer, William J. Spencer, Jillian N. Pearring
This study shows that peripherin-2's tetraspanin domain is essential for CNG channel localization to rod outer segments, and that ROM1 can compensate for its loss.
Molecular Biology of the Cell · Jul 1, 2026Peer-reviewedCell Biology