Insoluble Aβ overexpression in an App knock-in mouse model alters microstructure and gamma oscillations in the prefrontal cortex, causing anxiety-related behaviours
Eleftheria Pervolaraki, Stephen P Hall, Denise Foresteire, Takashi Saito, Takaomi C. Saido, Miles A. Whittington, Colin Lever, James Dachtler
This study shows that insoluble Aβ overexpression in AppNL-G-F mice causes prefrontal cortical changes linked to altered anxiety behaviors and gamma oscillations.
Disease Models & Mechanisms · Aug 22, 2019Peer-reviewedNeuroscience