Markov models of the apo-MDM2 lid region reveal diffuse yet two-state binding dynamics and receptor poses for computational docking
Sudipto Mukherjee, George A Pantelopulos, Vincent A Voelz
The paper uses Markov State Models to study apo-MDM2 dynamics, revealing two-state binding behavior and receptor conformations suitable for computational docking.
bioRxiv · May 16, 2016Biophysics