SARS-CoV-2 Omicron Spike Glycoprotein Receptor Binding Domain Exhibits Super-Binder Ability with ACE2 but not Convalescent Monoclonal Antibody
Olaposi Idowu Omotuyi, Olujide Oludayo Olubiyi, Oyekanmi Nash, Elizabeth Oluwatoyin Afolabi, Babatunji Emmanuel Oyinloye, Segun Fatumo, Mbang Nyong Femi-Oyewo, Suleiman Bogoro
This study investigates the interaction of the Omicron SARS-CoV-2 spike RBD with ACE2 and a neutralizing mAb, finding enhanced ACE2 binding and reduced mAb binding efficiency.
Computers in Biology and Medicine · Mar 1, 2022Peer-reviewedBioinformatics