Spatially-extended nucleation-aggregation-fragmentation models for the dynamics of prion-like neurodegenerative protein-spreading in the brain and its connectome
Sveva Fornari, Amelie Schäfer, Ellen Kuhl A, Alain Goriely
The paper models the spread of misfolded protein aggregates in the brain using nucleation-aggregation-fragmentation dynamics and network transport mechanisms.
Journal of Theoretical Biology · Dec 3, 2019Peer-reviewedNeuroscience