Author

Amelie Schäfer

Stanford UniversityORCID 0000-0002-4831-8961Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Alain GorielyiD· 2 shared Ellen Kuhl AiD· 2 shared Sveva Fornari· 2 shared Mathias JuckeriD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

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4 top collaborators · 6 mutual co-author links

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2 shared papersNeuroscience

Alain GorielyORCID

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2 papers

Recent·Most cited

NeuroscienceJournal of Theoretical BiologyPeer-reviewedDec 3, 2019

Spatially-extended nucleation-aggregation-fragmentation models for the dynamics of prion-like neurodegenerative protein-spreading in the brain and its connectome

Sveva Fornari, Amelie Schäfer, Ellen Kuhl A, Alain Goriely

The paper models the spread of misfolded protein aggregates in the brain using nucleation-aggregation-fragmentation dynamics and network transport mechanisms.

60 citationstop 4%

humanproteomics

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NeuroscienceJournal of The Royal Society InterfacePeer-reviewedOct 16, 2019

Prion-like spreading of Alzheimer's disease within the brain's connectome

Sveva Fornari, Amelie Schäfer, Mathias Jucker…·Ellen Kuhl A

This paper models prion-like spreading of Alzheimer's disease by integrating misfolding kinetics with a brain connectivity network derived from the Human Connectome Project, showing accurate predictions of neuropathology and simulating therapeutic strategies.

139 citationstop 2%

humanstatistical model

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