hnRNPA1 Remodels SARS-CoV-2 Genomic G-Quadruplexes through Its UP1 Domain
Parul Gupta, Swarnava Majumdar, Aditi Maulik, Mahavir Singh
This study identifies hnRNPA1 as a host factor that binds and remodels SARS-CoV-2 genomic G-quadruplexes through its UP1 domain, suggesting a mechanism for viral replication.
bioRxiv · Oct 16, 2026 · PreprintBiophysics