Adaptive Remodeling of the MPXV B21R Receptor-Binding Domain Enhances DC-SIGN Interaction and Identifies Conserved CTL Targets for T-Cell Vaccine Development
Swatantra Kumar, Arpita S. Harnam, Saurabh Kumar, Janusz Tadeusz Paweska, Ahmed Sayed Abdel-Moneim, Shailendra Kumar Saxena
This study analyzes the global epidemiology of Mpox and identifies mutations in the B21R protein that enhance DC-SIGN interaction and suggest T-cell vaccine targets.
bioRxiv · Mar 2, 2026 · PreprintMicrobiology