Computational design of membrane fusion proteins
Masaharu Somiya, Sydney Funk, Dane Evan Zambrano, Takumi Yanase, Noriyuki Hamaoka, Alex Kang, Banumathi Sankaran, Asim K. Bera, Neil P. King
This paper designs synthetic fusogens using machine learning, showing they enable efficient cell-cell and intracellular membrane fusion with higher activity than native SNARE complexes.
bioRxiv · May 7, 2026 · PreprintBiochemistry