Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery
B. Gotte, M. D. Panas, K. Hellstrom, L. Liu, B. Samreen, O. Larsson, T. Ahola, G. M. McInerney
This study shows that G3BP domains are required for alphavirus replication complex clustering and translation initiation, with SFV and CHIKV relying on different G3BP domains for replication.
bioRxiv · Apr 5, 2019Microbiology