Notch2 signaling guides B cells away from germinal centers towards marginal zone B cell and plasma cell differentiation
T. Babushku, M. Lechner, A. Yates, S. Rane, U. Zimber-Strobl, L. J. Strobl
The paper shows Notch2 signaling drives B cells from germinal centers to become marginal zone B cells or plasma cells, with mathematical modeling supporting this pathway.
bioRxiv · Jun 13, 2022Immunology