Decoding the comprehensive substrate-specificity and evidence of altered site-specific collagen prolyl-3-hydroxylation, lysyl-hydroxylation, and lysyl O-glycosylation in P4ha1 and P4ha2 deleted mutant mice
This study identifies site-specific collagen modifications in P4ha1 and P4ha2 mutant mice, revealing altered hydroxylation and O-glycosylation patterns affecting collagen biosynthesis and structure.
bioRxiv · Jun 28, 2023 · PreprintBiochemistry