The transcriptional repressor Zfp125 modifies hepatic energy metabolism in response to fasting and insulin resistance
G. W. Fernandes, B. M. L. C. Bocco, T. d. L. Fonseca, F. Salas-Lucia, O. Nickel, S. C. Russo, B. Gereben, I. C. Kettelhut, A. C. Bianco
This study shows that Zfp125 regulates hepatic energy metabolism by modulating gene expression related to fatty acid oxidation, ketogenesis, and gluconeogenesis, with implications for type 2 diabetes.
bioRxiv · Jul 2, 2020 · PreprintPhysiology