Characterizing glucokinase variant mechanisms using a multiplexed abundance assay
S. Gersing, T. K. Schulze, M. Cagiada, A. Stein, F. P. Roth, K. Lindorff-Larsen, R. Hartmann-Petersen
The paper characterizes mechanisms of human glucokinase variants by analyzing their abundance and stability, identifying residues that affect metabolic stability and conformational dynamics.
bioRxiv · May 24, 2023Biochemistry