T. K. Suresh Kumar

cpSRP43 is both highly flexible and stable: Structural insights using a combined experimental and computational approach

This study investigates the structural stability and flexibility of cpSRP43 using biophysical techniques and molecular dynamics simulations, revealing it is both highly stable and flexible.

Binding Affinity Estimation From Restrained Umbrella Sampling Simulations

The paper estimates protein-ligand binding affinity using restrained umbrella sampling simulations and compares results to experimental data.

Stability Comparisons between Natural versus Engineered Archaeal Heat Shock Proteins

This study compares the thermal and acid stability of natural and engineered archaeal heat shock proteins using structural and biochemical assays.

Mechanistic Picture for Monomeric Human Fibroblast Growth Factor 1 Stabilization by Heparin Binding

This study uses molecular dynamics simulations to show how heparin stabilizes hFGF1 by altering its conformational dynamics and electrostatic interactions.

Chloroplast SRP43 Subunit Prevents Aggregation of Proteins

This study shows that chloroplast SRP43 can act as a generic chaperone for non-LHCP proteins, preventing heat-induced aggregation and preserving bioactivity in some cases.