Author

T. Litfin

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Biology Disciplines

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Microbiology· 1

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Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Guo· 1 shared J. M. Atack· 1 shared L. Yang· 1 shared M. P. Jennings· 1 shared P. J. Blackall· 1 shared Y. Zhou· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

C. Guo

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1 paper

Recent·Most cited

Systematic analysis of REBASE identifies numerous Type I restriction-modification systems that contain duplicated, variable hsdS specificity genes that randomly switch methyltransferase specificity by recombination.

J. M. Atack, C. Guo, T. Litfin, L. Yang, P. J. Blackall, Y. Zhou, M. P. Jennings

The paper identifies 5.9% of Type I R-M systems with duplicated hsdS genes that enable phase-variation through recombination, found in pathogens like Enterococcus faecalis and Listeria monocytogenes.

bioRxiv · Jun 18, 2020Microbiology