Loss of Myosin-1e biases MMTV-PyMT induced breast cancer towards a 4 differentiated and secretory state
E. L. Plante, S. E. Chase, E. P. De Jong, T. M. Curtis, M. E. Garone, M. Krendel
This study shows that Myo1e depletion in breast cancer tumors shifts them toward a more differentiated, secretory state, while its presence promotes a less-differentiated, pro-tumorigenic state.
bioRxiv · Apr 27, 2022 · PreprintCancer Biology