Author

T. Palpant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

D. E. Shaw· 2 shared H. Xu· 2 shared C. Weinberger· 1 shared Q. Wang· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 5 mutual co-author links

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2 shared papersBiophysics

D. E. Shaw

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2 papers

Recent·Most cited

Design of antigens to present a tumor-specific cryptic epitope

H. Xu, T. Palpant, Q. Wang, D. E. Shaw

The paper designs antigens that present a tumor-specific cryptic epitope in the conformation recognized by mAb806, showing successful stabilization of the epitope in vitro.

bioRxiv · Apr 15, 2024 · PreprintBiophysics

Characterizing receptor flexibility to predict mutations that lead to human adaptation of influenza hemagglutinin

H. Xu, T. Palpant, C. Weinberger, D. E. Shaw

The paper uses molecular dynamics simulations to predict mutations in influenza hemagglutinin that enhance binding to human sialic acid receptors, validated by experiments.

Journal of Chemical Theory and Computation · Aug 9, 2022Peer-reviewedBiophysics