T. R. Booker

Spatial autocorrelation of the environment influences the patterns and genetics of local adaptation

This study shows that spatial autocorrelation in environmental variation influences the evolution and genetics of local adaptation through simulations and empirical analysis of lodgepole pine.

How useful is genomic data for predicting maladaptation to future climate?

The paper evaluates two methods for predicting population maladaptation to climate change using genomic data and finds they outperform climatic distances but have limited predictive consistency across future climates.

Novel reassortments of variation underlie repeated adaptation to whole genome duplication in two outcrossing Arabidopsis species

The paper identifies repeated selection signals in genes related to adaptation to whole genome duplication in two Arabidopsis species, showing that tetraploid-specific haplotype blocks arise from diverse allelic sources.

Using genome scans to identify genes used repeatedly for adaptation

This study introduces PicMin, a statistical method to test for repeated molecular evolution at the gene level using genome scan results, showing increased power with more lineages showing adaptation signals.

Background selection under evolving recombination rates

This study shows that evolving recombination rates modify background selection effects, potentially leading to underestimation of genome-wide selection impacts in house mice.

The WZA: A window-based method for characterizing genotype-environment association

The paper introduces the WZA method for GEA studies, which outperforms single-SNP approaches in detecting genotype-environment associations in heterogeneous environments.

Selective sweeps influence diversity over large regions of the mouse genome

This study estimates the effects of positive selection on protein-coding and regulatory mutations in wild mice, finding stronger fitness impacts from coding mutations but higher frequency in regulatory regions.

The genetics of assisted gene flow: immediate costs and long-term benefits

This study uses genetic simulations to evaluate the short-term and long-term effects of assisted gene flow on population fitness under climate change scenarios.

Inferring parameters of the distribution of fitness effects of new mutations when beneficial mutations are strongly advantageous and rare

This study shows that analyzing the unfolded site frequency spectrum (uSFS) underestimates positive selection strength when beneficial mutations are rare and strongly advantageous, suggesting caution in interpreting such data.

Variation in recombination rate affects detection of outliers in genome scans under neutrality

This study shows that recombination rate variation affects the distribution of FST in genome scans, leading to potential false positives and conservative results in low recombination regions.

Global adaptation confounds the search for local adaptation

This study shows that global adaptation can create FST outliers, potentially misleading interpretations of local adaptation in genome scans.

Understanding the factors that shape patterns of nucleotide diversity in the house mouse genome

The paper investigates how selection at linked sites affects nucleotide diversity in the house mouse genome using simulations and site frequency spectrum analysis.

The recombination landscape in wild house mice inferred using population genomic data

This study constructs a recombination map for M. m. castaneus and finds conservation of recombination rate variation with M. m. domesticus, along with a positive correlation between recombination rate and genetic diversity.