Novel AT1R-Allosteric Ligands Mask the Preeclampsia Auto-antibody Epitope and Decrease Angiotensin-induced Vasoconstriction
K. D. Singh, Z. P. Jara, T. Harford, P. P. Saha, T. R. Pardhi, R. Desnoyer, S. S. Karnik
The paper identifies novel AT1R allosteric ligands that block preeclampsia auto-antibody epitopes and reduce AngII-induced vasoconstriction.
bioRxiv · Apr 30, 2021Pharmacology & Toxicology