Systemic circulating microRNA landscape in Lynch syndrome
T. Sievänen, T.-M. Korhonen, T. Jokela, M. Ahtiainen, L. Lahtinen, T. Kuopio, A. Lepistö, E. Sillanpää, J.-P. Mecklin, T. T. Seppälä, E. K. Laakkonen
This study identifies circulating miRNA signatures in Lynch syndrome carriers that distinguish them from non-carriers but not from cancer patients, suggesting potential for monitoring oncogenic stress in cancer-free individuals.
bioRxiv · Mar 10, 2022Cancer Biology